Are these actually the same, similar or different?
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Uridine, Pseudouridine, N1-methylpseudouridine are not the same. Psuedouridine- psuedouridine synthase rotates the uracil section 180 degrees. Moved 3 carbons over and rotated 180 degrees. Pseudouridine is not N1-Methylpseudouridine. A methyl has been added to N1 position. Pseudouridine is found and can be used as a biomarker in prostate cancer (Uddin 2020)(Uddin, M. B., Wang, Z., & Yang, C. (2020). Dysregulations of Functional RNA Modifications in Cancer, Cancer Stemness and Cancer Therapeutics.
Are these actually the same, similar or different?
Are these actually the same, similar or…
Are these actually the same, similar or different?
Uridine, Pseudouridine, N1-methylpseudouridine are not the same. Psuedouridine- psuedouridine synthase rotates the uracil section 180 degrees. Moved 3 carbons over and rotated 180 degrees. Pseudouridine is not N1-Methylpseudouridine. A methyl has been added to N1 position. Pseudouridine is found and can be used as a biomarker in prostate cancer (Uddin 2020)(Uddin, M. B., Wang, Z., & Yang, C. (2020). Dysregulations of Functional RNA Modifications in Cancer, Cancer Stemness and Cancer Therapeutics.